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FAQs and other information

The side effects

Very few people experience side effects. The reported side effects include occasional episodes of:

  • Mild headache.

  • Slight nausea, no vomiting.

  • Soft stool or loose stool with no cramping.

  • Transient increases in anxiety or irritability an hour after initiating treatment, which resolves after an hour or so.

  • Insomnia, which can be corrected by lowering the dose or taking the product no later than midday.

  • A feeling of sedation, which can be corrected by taking the product as a single 50mg dose at night.

NO severe adverse effects from using Release Sce-Forte have been documented.


There have been no confirmed reports of drug interactions. However, because of the neuro-receptor activities of sceletium tortuosum, there may be interactions with other pharmacokinetic drugs.


People taking any psychiatric drug (including all anti-anxiety drugs, sedatives, hypnotics, anti-depressants, anti-psychotics and so-called “designer” or recreational drugs) or any cardiac medications, are advised not to take sceletium tortuosum-containing products without their medical doctor’s assistance.


As with most supplements and modern drugs, safety in pregnancy for Release_SCE has not been established.

  • Can I use ReleaseSCE™ FORTE with Ritalin / Concerta / Neovision / Straterra or chemical SSRI’s?
    Many people and parents have had success with either alternating doses of ReleaseSCE™ with existing medication until weaned off or replacing the medication with ReleaseSCE™. The ReleaseSCE™ formula with the added chelated minerals, amino acids, and vitamins helps improve memory, mood and the vitality of your brain and mind. At the same time, it acts as a potent antioxidant, an anti-inflammatory, and an immunity enhancer. It can increase serotonin uptake in some brain regions and can improve the spatial memory effect. It can assist in regulating the body’s natural blood-sugar levels and facilitates the absorption of glucose into brain cells.
  • Can ReleaseSCE™ FORTE replace chemical ADHD medication?
    Many pupils, and parents have done it and have not looked back. Tell your doctor about the ReleaseSCE™ range and ask your doctor to investigate the possible change. The ReleaseSCE™ range is a one-of-its-kind formula and linked data shows that it can boost the brain with all the vital elements and improve your cognition daily. It protects your brain and nervous system from harmful chemical cytokines and chemical imbalances.
  • What are the side effects of ReleaseSCE™ FORTE?
    Very few people experience side-effects. The reported side-effects include occasional episodes of: mild headache; slight nausea, no vomiting; soft stool or loose stool with no cramping; transient increase in anxiety or irritability an hour after initiating treatment, which resolves after an hour or so; insomnia, which can be corrected by lowering the dose or taking the product not later than midday; a feeling of sedation, which can be corrected by taking the product as a single 50mg dose at night NO severe adverse effects have been documented from using ReleaseSCE™ FORTE.
  • What are the long-term effects of ReleaseSCE™ FORTE?
    The ReleaseSCE™ range formula was created to give the sufficient doses of each element needed, under the safety regulations linked to the recommended safety data on each individual combination of the ingredients, to enhance and maintain the intended function, and to be safe to use over long periods of time. False data written by an independent author was released on certain websites regarding the quality and the safety of the SSRI functionality in Sceletium ( Kanna ) unfortunately other kanna / sceletium selling companies have copied that data and shared it on their sites too.The outcome, false data contradicting itself and the clinical data they based the information on was a study conducted between SSRI’s ( selective serotonin re-uptake inhibitors ) , MAOI’s( Monoamine oxidase inhibitors) , and MDMA (Methylenedioxymethaphetamine). This study was done for a drug called Fluoxetine, a variant of Prozac – both Scheduled 4. The outcome of this study was projected as a contraindication to the SSRI element in the Sceletium Tortusuom plant for the safety there of. Unfortunately, this data was shared and created a false image of the wonderful power the Sceletium plant has. It is true that there was a lack of evidence on the safety of the natural SSRI ability in the Sceletium plant when used with scheduled SSRI’s or Neuro Recreational drugs. The recent studies on Sceletium have proven that this natural product is a rich source in therapeutic agents. It was based on the extraction, isolation, identification, and pharmacological research on the alkaloids from Sceletium tortuosum. Sceletium tortuosum and its alkaloids can act as PDE4 and 5-TH inhibitors to improve memory and improve cognition. It acts as an anti-anxiety and anti-depressant synergist as a PDE4 and serotonin reuptake inhibitor, and also acts as a monoamine releasing agent to slightly inhibit monoamine oxidase type A activity. It regulates anxiety by regulating related hormones and produces antidepressant activity. At high doses combined with GABA and opioid receptors, it can relieve anxiety symptoms. Sceletium tortuosum improves sleep quality by regulating the sleep-wake cycle by regulating the PDE4-cAMP-CREB signaling cascade. It also reduces pain-related δ, α2 and β1 attenuation associated θ waves to exert analgesic effects and does not produce addiction due to non-inhibition of dopamine transporter. In addition, it has a certain potential for epilepsy treatment because of its action on AMPA-mediated transmission. Pei Yu Journal of Pharmaceutical and Biomedical Sciences Sceletium tortuosum and its pharmacological activity VOL 10, ISSUE 06, YEAR 2020 157 Sceletium tortuosum may be involved in a variety of neurodegenerative diseases, chronic diseases, for the targeting of the central nervous system. The related pharmacological effects have been demonstrated by experiments. It has played a certain role in neurological diseases. The alkaloids of Sceletium tortuosum exerted cellular protective and anti-inflammatory effects and exhibited effective antioxidant effects to maintain the integrity of the central nervous system, which may be employed as either a preventative supplement or complimentary treatment in the context of obesity and diabetes 4. Nowadays, people face increasing levels of stress, anxiety, insomnia and depression. Elderly people are particularly susceptible to diseases such as cognitive memory disorders, Alzheimer’s disease, vascular dementia, Parkinson’s disease and so on. Excitingly, animal and human studies of Sceletium tortuosum have showed an excellent safety profile. At the same time, preliminary human studies and clinical experience have shown its therapeutic efficacy in anxiety, depression, cognitive impairment and so on. The conclusion is that it is never safe to just leave or change your scheduled medication without a medical practitioners opinion. The higher doses of the serotonin releasing agents might have an effect if you use Release-SCE at higher doses with your prescribed SSRI’s or any other prescribed scheduled medication. The answer would be to start substituting with a dual dose, and transferring to the more safe alternative with the help of your medical practitioner.
  • What is the best time to take ReleaseSCE™ FORTE?
    The best time to take ReleaseSCE™ is every morning with breakfast and, if needed, a top up dose late afternoon. It is always best to take it before, or with a meal.
  • Why is this product not in Clicks or Dischem?
    Our business model was built with distributing representative agents, all of whom have a story to tell, on their great results. It is important for us to keep our personal touch with our products. Our mission has always been to help as many people as we can, and a network of distributing agents, independent pharmacies and health shops works very well for us. We prefer the personal approach and have been able to improve many more people’s lives. A shelf in a pharmacy cannot share the story behind the product, and there are many sceletium products on the shelves that will not give the intended results. The ReleaseSCE™ range is one of a kind, and the best is to use it yourself to see why we are so proud of this product.
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